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getEmpiricalFDR

getEmpiricalFDR.Rd

Computes the FDR as the proportion of negative peaks with a more extreme p-value, eventually extrapolating and preserving the ranking.

Usage

getEmpiricalFDR(log10p, pneg, n = length(log10p) * 10)

Arguments

log10p

-log10 p-values of candidate peaks

pneg

-log10 p-values of negative peaks

n

The number of hypotheses (used when the empirical FDR is zero)

Value

A data.frame with the empirical FDR and a smoothed -log10(FDR)